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you cannot cast it without sacrificing a creature, and you cannot sacrifice additional creatures

After you move your venture marker into the last room of a dungeon and that room's ability resolves (or otherwise leaves the stack), the dungeon leaves the game and you have now completed it

Craterhoof Behemoth is the gold standard, but pretty much any of these effects are good

It's actually more surprising that Emrakul, the definite strongest among the three Eldrazis, isn't making the headlines, but it's never a surprise that one of the three is on the list

As for the Mythic Invitational itself, I would call the event a modest success

Creature - Giant