Arceus has filled that void nicely, and since it's a basic Pokmon, that leaves plenty of room for support cards
If Jenova dies at the same time as one or more Mutants you control, its last ability will trigger for each of those Mutants (including itself if it somehow became a mutant)
Many defender decks love this card, and many toughness-based interactions love to use it instead of something like Tree of Perdition
If you use Tormod's Crypt with Creeping Chills trigger on the stack you will prevent them from having the option of exiling it meaning it will not damage you
Red acts on impulse and emotion, translating to haste creatures, burn spells, and effects that sacrifice long-term value for immediate impact
Since cycling generally costs one or two mana, no matter what cycling creature you end up hitting with Unpredictable Cyclone, you'll come out way ahead in terms of mana, paying two for a four-, five-, or even seven-drop, which sort of puts Unpredictable Cyclone into the Wilderness Reclamation / Fires of Invention category of absurdly powerful ramp spells that only work in fairly specific decks